Inhibitor of cathepsins B and L; also thought to inhibit calpain. Inhibits lysosomal proteases and interferes with autolysosomal digestion when used in combination with pepstatin A (Cat. Keywords: E 64d, E 64d supplier, lysosomal, proteases, inhibitors, inhibits, cathepsins. Cell-permeable, ethyl ester of Ec. The ester is hydrolyzed by intracellular esterases to produce Ec. Inhibits calpain and cathepsins B, H, and L. Inhibits . Membrane-Permeant Cysteine Protease Inhibitor E64d. S. Eksi,1 B. Czesny,1 G.- J. . or without protease inhibitors, M E64d (Sigma, St Louis, MO), 10 M.
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E 64d Supplier | CAS | E64d | Tocris Bioscience
Our New Product guide highlights over new products added in the second half of sigmq References References are publications that support the biological activity of the product. Published data Date published: Volume nanoliter microliter milliliter liter.
In addition, Ed has been shown to induce cell cycle arrest during prophase and metaphase in Xenopus embryonic cells. Santa Cruz Biotechnology, Inc. Inhibits degradation of autophagic cargo inside autophagolysosomes. Please sign in using your account on one of the following social networks. Do you know of a great paper that uses E 64d from Tocris? Please provide sogma valid email address. Why create an account? Flying Start New Lab Program. Mass in vial mg ug ng. Cathepsin inhibitor; interferes with autolysosomal digestion.
Why Do You Research? Our new product guide highlights over new products added to the Tocris Bioscience range during the second half of Autophagy 1 84 PMID: Already have an account? Acta, Application s: Concentration femtomolar picomolar nanomolar micromolar millimolar molar. New Gene Target to Prevent Obesity. Concentration 2 femtomolar picomolar nanomolar micromolar millimolar molar.
E-64-d (CAS 88321-09-9)
Kim et al Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer. Autophagy 4 PMID: Certificate of Analysis Catalog Number sc scA.
Creating an account with us makes your shopping experience much easier and faster. Tocris products are intended for laboratory research use only, unless stated otherwise. Have you used E sigmaa Cell-permeable, ethyl ester of Ec.
Ed | CAS | SCBT – Santa Cruz Biotechnology
Exercise Can Reprogram the Brain. Sign Up for Santa Cruz Biotechnology news and announcements. For batch specific data refer to the Certificate of Analysis.
The ester is hydrolyzed by intracellular esterases to produce Ec. Mutants of collagen-specific molecular chaperone Hsp47 causing osteogenesis imperfecta are structurally unstable with weak binding affinity to collagen: Citations 1 to 6 of 6 total Display: Concentration 1 femtomolar picomolar nanomolar micromolar millimolar molar. E 64d, E 64d supplier, lysosomal, proteases, inhibitors, inhibits, cathepsins, autophagy, autolysosomal, digestion, E64d, Autophagy, Calcium-Sensitive, Proteases, Cathepsin,Tocris Bioscience.
Journal of immunology Baltimore, Md. Proteomic analysis of silenced cathepsin B expression suggests non-proteolytic cathepsin B functionality: Ed, sc, is a white solid. Flow Cytometry Spectra Viewer. The following data is based on the product molecular weight Email address is required. Submit a review and receive an Amazon gift card. Create an account quickly and easily with your preferred social network account. Not Intended for Diagnostic or Therapeutic Use. Ito, et al; Biochem. What is the appearance of the compound?
Solubility Data Solvent Max Conc. See how others have used Ed.